Harmon Wildlife Area is located on the Neosho River floodplain. A river oxbow with permanent water is surrounded on three sides by bottomland hardwoods. The remaining is undisturbed native prairie. Labette creek borders a .2-mile section on the west side of the property.
The undisturbed prairie meadow is noted for its wildflower diversity. The mature woodland dominated by oaks, hickory and walnut is indicative of the rich bottomland soil.
Species hunted include whitetail deer, eastern turkey, fox squirrel and cottontails.
Fishing opportunities are limited due to hike-in only access. Fish species include channel catfish, white crappie, green sunfish and rough fish.
Principal management practices on the area include prescribed burns and wildlife plantings. The property is managed with federal wildlife restoration money, state wildlife fee fund money and from agricultural income generated on the property.