Paint Creek Lake Wildlife Area is located in southwest Ohio, at the south edge of Greenfield on the Paint Creek fork and the southeast edge of Centerfield on the Rattlesnake fork of Paint Creek Lake. State Routes 138 and 753 bisect the Rattlesnake fork approximately 15 miles east of Hillsboro. The area may be reached by turning north off U.S. 50 onto State Route 753 or onto Rapid Forge Road in Ross County. The 5,090-acre wildlife area lies at the upper end of Paint Creek Lake, a flood control reservoir operated by the U.S. Army Corps of Engineers. In summer, the reservoir is normally 1,170 acres with 25 miles of shoreline. During periods of heavy rainfall, the reservoir covers portions of the wildlife area that are normally dry. Paint Creek State Park, 5,934 acres, lies south of the wildlife area on both sides of the reservoir. Meadow and grain crops make up about one-third of the wildlife area. The remainder of the wildlife area is about equally divided in woodland and reverting fields of shrubs, small trees, grasses, and forbs.