Pickerel Creek Wildlife Area lies between the south shore of Sandusky Bay and U.S. Route 6 in Townsend and Riley townships, Sandusky County. The area totals 3,200 acres. The majority of the area has been restored to wetland with the remainder in woods, brush, and native grassland. Pickerel Creek flows through the western half of the area, forming a high quality freshwater estuarine habitat.